Get your custom NGS panel in 4 weeks

Easily build a CleanPlex Custom NGS Panel to accelerate your research and assay development. Multiplex up to 20,000+ amplicons in each reaction and take advantage of CleanPlex Technology’s high sensitivity, rapid single-tube workflow, and cost-effective sequencing.

Use ParagonDesigner, our free, web-based tool, to submit your target regions of interest and instantly receive a design coverage report to review. Our custom panel design experts will be available through the process to provide you a quote, help you with any questions, and make further optimization to meet your needs. Once you approve the design, your custom NGS panel will be ready for shipment in 4 weeks.

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Build better and smarter NGS assays

CleanPlex® Custom NGS Panels are powered by Paragon Genomics’ CleanPlex Technology – an ultra-high multiplex PCR-based target enrichment technology for next-generation sequencing (NGS). It features a highly advanced proprietary primer design algorithm and an innovative, patented background cleaning chemistry. Together, they allow CleanPlex Custom NGS Panels to break the limits of existing target enrichment technologies.

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Enjoy the highest level of personalization

Our expert scientists are ready to design and optimize CleanPlex Custom NGS Panels to meet your desired specifications. CleanPlex Custom NGS Panels are designed using Paragon Genomics’ proprietary ParagonDesigner™ algorithm and iteratively optimized in-silico to ensure success of your NGS-based assays. Amplicon size can tailored for your sample types according to your specified input DNA fragment size to generate the highest level of performance.

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Build your panel faster on top of Paragon curated gene content

To speed up your custom NGS assay development, our team has consulted with leading experts and curated relevant gene content for specific applications such as cardiac diseases and neurodegenerative diseases. These pre-designed panels have already been evaluated in silico and can be made to order fast. You have the option to add new content or modify the existing content of these panels. 

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Why Choose CleanPlex Custom NGS Panels?

Design Custom NGS Assays Online with ParagonDesigner

Get your answers sooner! Using the ParagonDesigner online portal to create a new CleanPlex Custom NGS Panel is quick and easy. Just follow 3 simple steps and our intuitive user interface will guide you through the process. Our design experts will be available to answer your questions, implement additional customization, and provide you a quote.

Remember to register before you begin. We just need a few basic information so we can create an account for you to view and track your designs. We promise signing up will be a breeze!

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More Than 3,400 Clinically-Relevant Genes with Pre-Designed Solutions

ParagonDesigner features a database of more than 3,400 human genes that have been pre-designed using our advanced primer design algorithm to allow custom gene panels to be created instantly. The database includes genes associated with both rare and common cancers, as well as all guideline-recommended genes in solid tumors, hereditary cancers and genetic disorders including those with companion diagnostic indications.

» Explore the Entire List

customer testimonial UCSF logo

When we decided to choose a sequencing platform, we had several choices and I am delighted that we chose Paragon Genomics. Paragon Genomics has enabled us to move our sequencing in-house with an affordable and easy-to-use product. They assisted us every step along the way from choosing the amplicons, to guiding us through library preparation to assisting with analysis. I strongly recommend their CleanPlex® amplicon-based targeted sequencing approach and could not be happier with their product.

Elliot Stieglitz, MD, Assistant Professor, University of California San Francisco

Need Functional Validation?

Our expert scientists are here to support you from design to validation for your assay development project. Paragon Genomics provides extensive wet-lab validation and optimization to ensure optimal performance of your assay on your specified sample type and quick transition of the assay into your lab.

What’s Included in My CleanPlex Custom NGS Panel?

Each CleanPlex Custom NGS Panel contains all reagents necessary to construct target-enriched, sequencing-ready NGS libraries from input DNA. Your CleanPlex Custom NGS Panel will include a CleanPlex Targeted Library Kit, your custom multiplex PCR primer mix, CleanMag® Magnetic Beads for bead purification, and Illumina® or Ion Torrent index primers for multiplexing and sequencing on the platform of your choice.

Request a Free Custom Panel Design Consultation

Not ready to design a custom panel? 

Enter your email below to schedule a free consultation with our PhD-level expert scientists to learn how our best-in-class custom panel design services can help you advance your work.