Over 1600 Custom NGS Panels (Next-Generation Sequencing Assays) including both DNA and RNA panels have been expertly designed and shipped to hundreds of NGS labs globally for research and testing applications ranging from tumor profiling, cancer liquid biopsy, pharmacogenomics, neurology, cardiology, infectious disease to food safety and agrigenomics.


Get your custom NGS panel or sequencing panel in 4 weeks

Easily build a CleanPlex Custom NGS or Sequencing Panel to accelerate your research and assay development. Multiplex up to 20,000+ amplicons in each reaction and take advantage of CleanPlex Technology’s high sensitivity, rapid single-tube workflow, and cost-effective sequencing.

Use ParagonDesigner, our free online multiplex PCR primer design tool, to submit your target regions of interest and instantly receive a design coverage report to review. Once you approve the design, your custom NGS amplicon panel will be ready for shipment in 4 weeks.

» Start designing now and obtain a quote 


Build better and smarter NGS assays

CleanPlex® Custom NGS Amplicon Panels are powered by Paragon Genomics’ CleanPlex NGS Amplicon Sequencing Technology – an ultra-high multiplex PCR-based target enrichment technology for next-generation sequencing (NGS). It features a highly advanced proprietary primer design algorithm and an innovative, patented background cleaning chemistry. Together, they allow CleanPlex Custom NGS Amplicon Panels to break the limits of existing target enrichment technologies (Read this blog article about how). 

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Enjoy the highest level of personalization

Our expert scientists are ready to design and optimize CleanPlex Custom NGS Panels to meet your desired specifications. CleanPlex Custom NGS Panels are designed using Paragon Genomics’ proprietary ParagonDesigner™ algorithm and iteratively optimized in-silico to ensure success of your NGS-based assays. Amplicon size can tailored for your sample types according to your specified input DNA fragment size to generate the highest level of performance.

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Build your NGS sequencing panel faster on top of Paragon curated gene content

To speed up your custom NGS assay development, our team has consulted with leading experts and curated relevant gene content for specific applications such as cardiac diseases and neurodegenerative diseases. These pre-designed NGS panels have already been evaluated in silico and can be made to order fast. You have the option to add new content or modify the existing content of these panels. 

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Why Choose CleanPlex Custom NGS Sequencing Panels?

Design Custom NGS Assays Online with ParagonDesigner

Get your answers sooner! Using the ParagonDesigner online portal to create a new CleanPlex Custom NGS Panel is quick and easy. Just follow 3 simple steps and our intuitive user interface will guide you through the process. Our design experts will be available to answer your questions, implement additional customization, and provide you a quote.

» Start Designing Now

When we decided to choose a sequencing platform, we had several choices and I am delighted that we chose Paragon Genomics. Paragon Genomics has enabled us to move our sequencing in-house with an affordable and easy-to-use product. They assisted us every step along the way from choosing the amplicons, to guiding us through library preparation to assisting with analysis. I strongly recommend their CleanPlex® amplicon-based targeted sequencing approach and could not be happier with their product.

Elliot Stieglitz, MD, Assistant Professor, University of California San Francisco

Need Functional Validation?

Our expert scientists are here to support you from design to validation for your assay development project. Paragon Genomics provides extensive wet-lab validation and optimization to ensure optimal performance of your custom NGS assay on your specified sample type and quick transition of the assay into your lab.

What’s Included in My CleanPlex Custom NGS Panel?

Each CleanPlex Custom NGS Panel contains all reagents necessary to construct target-enriched, sequencing-ready NGS amplicon libraries from input DNA. Your CleanPlex Custom NGS Panel will include a CleanPlex Targeted Library Kit, your custom multiplex PCR primer mix, CleanMag® Magnetic Beads for bead purification, and Illumina® or Ion Torrent index primers for multiplexing and sequencing on the platform of your choice.

Request a Free Custom Sequencing Panel Design Consultation

Enter your email below to schedule a free consultation with our PhD-level expert scientists to learn how our best-in-class custom NGS panel design services can help you advance your precision medicine testing and research.