Product Description
The CleanPlex for MGI BRCA1 & BRCA2 Panel is a multiplex PCR-based targeted resequencing assay designed to simplify the evaluation of somatic and germline variants across BRCA1 and BRCA2 genes on DNBSEQ™ platforms. The panel targets all exonic regions and flanking intronic sequences of BRCA1 and BRCA2. Starting with just 20 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The panel is optimized to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.
Highlights
- Sensitive Detection
Detect somatic mutations as low as 1% variant allele frequency using just 20 ng of DNA - Fast, Streamlined Workflow
Generate sequencing-ready libraries in just 3 hours using a rapid, three-step protocol - Superb Performance
Prepare high-quality NGS libraries with excellent on-target performance using CleanPlex Technology to enable efficient use of sequencing reads and reduce costs
The CleanPlex for MGI BRCA1 & BRCA2 Kit contains CleanPlex for MGI Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex for MGI Indexed PCR Primers and CleanMag® Magnetic Beads are ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.
Paragon Genomics has partnered with VarSome Clinical to provide a full solution for fast and accurate variant discovery, annotation, and interpretation of next-generation sequencing data for targeted gene panels. Click here to find out more!
Storage Temperature
Store at -20 °C.
For Research Use Only. Not for use in diagnostic procedures.