The CleanPlex for MGI BRCA1 & BRCA2 Panel is a multiplex PCR-based targeted resequencing assay designed to simplify the evaluation of somatic and germline variants across BRCA1 and BRCA2 genes on DNBSEQ™ platforms. The panel targets all exonic regions and flanking intronic sequences of BRCA1 and BRCA2. Starting with just 20 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The panel is optimized to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.

Highlights

• Sensitive Detection
  Detect somatic mutations as low as 1% variant allele frequency using just 20 ng of DNA
• Fast, Streamlined Workflow
  Generate sequencing-ready libraries in just 3 hours using a rapid, three-step protocol
• Superb Performance
  Prepare high-quality NGS libraries with excellent on-target performance using CleanPlex Technology to enable efficient use of sequencing reads and reduce costs

The CleanPlex for MGI BRCA1 & BRCA2 Kit contains CleanPlex for MGI Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex for MGI Indexed PCR Primers and CleanMag^® Magnetic Beads are ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.

Paragon Genomics has partnered with VarSome Clinical to provide a full solution for fast and accurate variant discovery, annotation, and interpretation of next-generation sequencing data for targeted gene panels. Click here to find out more!

Storage Temperature

Store at -20 °C.

For Research Use Only. Not for use in diagnostic procedures.