Homepage 2018-11-08T17:21:35+00:00

NEW! Easily and quickly design custom NGS assays online with ParagonDesigner™ – LEARN MORE

NEW! CleanPlex® UMI Lung Cancer Panel for confident detection of low-frequency variants – LEARN MORE

CleanPlex® Custom NGS Panels

Submit a design online and get your custom NGS panel in 2 weeks!


CleanPlex® Custom NGS Panels are designed and optimized by our expert scientists to meet the desired specifications using Paragon Genomics’ proprietary ParagonDesigner algorithm. Powered by our patented CleanPlex chemistry, as many as 20,000+ amplicons per primer pool can be multiplexed in a single reaction to create small to large panels for any applications and for either Illumina® or Ion Torrent platforms. In addition, amplicon size can be tailored according to input DNA fragment size to generate optimal performance for all sample types.


When we decided to choose a sequencing platform, we had several choices and I am delighted that we chose Paragon Genomics. Paragon Genomics has enabled us to move our sequencing in-house with an affordable and easy-to-use product. They assisted us every step along the way from choosing the amplicons, to guiding us through library preparation to assisting with analysis. I strongly recommend their CleanPlex® amplicon-based targeted sequencing approach and could not be happier with their product.

Elliot Stieglitz, MD, Assistant Professor, University of California San Francisco

CleanPlex® Ready-to-Use NGS Panels

Fast and accurate analysis using pre-designed and pre-optimized panels


CleanPlex® Ready-to-Use NGS Panels are designed and optimized using content from peer-reviewed publications and expert input. These pre-optimized panels target the most important and meaningful variants in the area of interest and are compatible with gDNA, FFPE DNA, and cDNA. CleanPlex Ready-to-Use Panels are powered by Paragon Genomics’ patented CleanPlex technology, which uses a novel multiplex PCR background cleaning chemistry to effectively remove non-specific PCR products, resulting in high level of on-target and coverage uniformity performance and efficient use of sequencing reads. All panels feature a simple, streamlined, three-step protocol that can be completed in just 3 hours, allowing you to get to results faster!  


CleanPlex® Technology

The most advanced amplicon-based target enrichment technology


CleanPlex® technology uses a proprietary multiplex PCR background cleaning chemistry to effectively remove non-specific PCR products and primer-dimers. CleanPlex’s ultra-high multiplexing chemistry allows more than 20,000 amplicons to be multiplexed in a reaction. High quality target-enriched NGS libraries are generated in just 3 hours using a streamlined, 3-step workflow, allowing researchers and assay developers to discover more with less.


Sign Up for Product and Event Updates