CleanPlex^® NGS Panels for Targeted Sequencing

CleanPlex^® ready-to-use and custom NGS panels are designed and optimized by our expert scientists to meet the desired specifications using Paragon Genomics’ proprietary ParagonDesigner^™ algorithm. CleanPlex^®amplicon size can be tailored according to input DNA fragment size to generate optimal performance.

Ready-to-Use Panels

Ready-to-use panels are designed and optimized using content from peer-reviewed publications and expert input. These pre-optimized panels target the most important and meaningful variants in the area of interest and are compatible with gDNA, FFPE DNA, and cDNA.

Custom Panels

Custom panels are made-to-order with fast turn-around time to target genomic regions of your interest and are available for human and other species. Our PhD level expert scientists provide best-in-class technical support to ensure your custom panels meet the desired specifications.

Discover more with less using CleanPlex^® NGS Panels

CleanPlex^® technology uses a proprietary multiplex PCR background cleaning chemistry to effectively remove non-specific PCR products and primer-dimers. High quality target-enriched NGS libraries are generated in just 2.5 hours using a streamlined, single-tube, 3-step workflow, allowing researchers and assay developers to discover more with less.

Discover More with CleanPlex® NGS Panels

Multiplex up to 20,000 amplicons per reaction

High target design rate

High coverage uniformity and on-target rate

High sensitivity (1% LOD with 10 ng input)

Use Less with CleanPlex® NGS Panels

Inputs as low as 100 pg of DNA

Fast 2.5-hour protocol

Simple single-tube workflow

Efficient use of NGS reads

Experience the CleanPlex^® advantages for yourself but also hear from our users

“Superb technical and customer support combined with fast design resulted in a high-quality NGS custom panel. CleanPlex technology is fast and easy to use with great PCR uniformity and on-target rate.”

Chongjian Chen, PhD , CEO of Annoroad

“Fruit and vegetable industries in the continental US are under constant threat by invasive pest fruit flies, many of which cannot be identified using morphology alone. When flies or their larvae are intercepted, regulatory agencies need to quickly identify what species they are dealing with and where they came from. USDA-ARS and University of Hawaii are developing genomic tools for these tasks. Paragon Genomics CleanPlex technology allows us to target thousands of highly-informative genomic regions is a single panel, thus integrating species identification and source determination. The 2.5-hour library preparation time combined with robust reaction chemistry for low quality samples means that these tools can be used quickly and efficiently.”

Julian R. Dupuis, Ph.D, Junior Faculty, University of Hawaii at Manoa and USDA-ARS

“We are looking for a ‘future proof method’, a better way to do high throughput screening at a species level diagnosis. Paragon Genomics has developed a rapid 2.5-hour library preparation allowing multi-gene methodology, letting us look at lots of unique loci across multiple genomes. It offers a ‘one and done’ approach instead of many different disconnected experiments”

Scott Geib, PhD, Research Entomologist at USDA-ARS

“As a service provider and distributor company, it is crucial for us to fulfil inquiries coming from our customer in a fast and reliable manner. Paragon Genomics’ custom design and production pipeline has shown itself very useful to expand our portfolio and services in a very short time. Their CleanPlex assays are robust and work directly from the start with a uniform coverage distribution and the ability to design single gene or small gene panels as well as larger panels makes CleanPlex a flexible tool.”

Damla Erdogan, Business Development Manager at Gen Era Diagnostik