NGS Panels for Precision Medicine and Research

CleanPlex® is the most advanced amplicon-based target enrichment technology. Start a new design and accelerate the development of your NGS assay.

CleanPlex® Ready-to-Use NGS Panels

Accurate detection of somatic and germline mutations

Powered by a novel multiplex PCR background cleaning chemistry to effectively remove non-specific PCR products, resulting in high level of on-target and coverage uniformity performance and efficient use of sequencing reads.


CleanPlex® UMI Ready-to-Use NGS Panels

Precise analysis of low-frequency variants

Incorporates unique molecular identifiers (UMIs) to enable error correction and are designed to work with cell-free DNA (cfDNA) and FFPE DNA for liquid biopsy and tumor profiling applications. 


CleanPlex® Custom NGS Panels

Submit a design online and get your custom NGS panel in 4 weeks!

Designed and optimized by our expert scientists to meet your desired specifications. As many as 20,000+ amplicons per primer pool can be multiplexed in a single reaction to create small to large panels for any applications and for Illumina®, BGI/MGI, or Ion Torrent™ platforms. 


ParagonDesigner™ Custom NGS Assay Design Tool

Have a project in mind already? Use ParagonDesigner, our free, web-based NGS assay design tool, to submit your target regions of interest and instantly receive a design coverage report to review. Once you approve the design, your custom NGS panel will be ready for shipment in 4 weeks.

Meet with us at ACMG 2020

Visit our Booth at the 2020 ACMG Annual Clinical Genetics Meeting
San Antonio, Texas USA, March 17 – 21, 2020

Learn More


A Universe of Possibilities

Solid Tumor Profiling

Hematologic Cancer Profiling

Liquid Biopsy – cfDNA Analysis

Liquid Biopsy – CTC Analysis

Cancer Risk Assessment

Tumor Mutational Burden

Genetic Disorders

Pharmacogenomics Profiling

CRISPR Editing Assessment

Molecular Breeding

Customer Success Story

When we decided to choose a target enrichment platform, we had several choices and I am delighted that we chose Paragon Genomics. Paragon Genomics has enabled us to move our sequencing in-house with an affordable and easy-to-use product. They assisted us every step along the way from choosing the amplicons, to guiding us through library preparation to assisting with analysis. I strongly recommend their CleanPlex® amplicon-based targeted sequencing approach and could not be happier with their product.

Elliot Stieglitz, MD, Assistant Professor, University of California San Francisco

Who’s Choosing CleanPlex

Researchers and assay developers from organizations, large and small, are expanding their genomics capabilities with CleanPlex

Upcoming Events

Meet us at upcoming events and learn how we can help you discover MORE with lessTM

2020 AGBT Annual Meeting
Feb 23 – 26, 2020, Palm Springs, CA

2020 ACMG Annual Clinical Genetics Meeting
Mar 17 – 21, 2020, San Antonio, TX