The CleanMag^® Magnetic Beads offer a highly consistent solution for reaction purification and are developed for use in targeted library construction using CleanPlex^® and CleanPlex UMI NGS Panels. CleanMag Magnetic Beads are formulated in a buffered solution to quickly bind PCR amplicons and other DNA products above 100 bp, allowing for the removal of excess primers, nucleotides, salts, and enzymes.  The reversible nature of the binding interaction between beads and PCR amplicons enables easy elution and separation following purification.

Highlights

• Seamless Integration into CleanPlex Workflows
  Compatible and validated with all CleanPlex and CleanPlex UMI targeted library preparation protocols
• Versatile
  Compatible with a variety of DNA and RNA NGS library preparation chemistries, as well as manual and automated processing.
• High Performance
  Fast, consistent, and efficient purification with high recovery performance comparable to Agencourt^® AMPure^® XP beads

Storage Temperature

Store at 2-8 °C. Do NOT freeze.

Handling and Use

To prevent contamination of the CleanMag Magnetic Beads, use sterile laboratory techniques when handling the product.  Allow the product to equilibrate to room temperature before use and always vortex the solution vigorously prior to use to thoroughly resuspend the beads.

The volumetric ratio of the CleanMag Magnetic Beads solution to sample is critical to the size-selection performance. Ensure accurate aspiration and dispensing of the magnetic beads solution by pipetting slowly and wiping droplets of magnetic beads off the outside of the pipette tip.

For Research Use Only. Not for use in diagnostic procedures.