The CleanPlex® Comprehensive Hereditary Cancer Panel is a pre-designed and stocked multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 88 genes associated with Comprehensive Hereditary Cancer. The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.

The panel kit contains CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.