CleanPlex® Comprehensive Genetic Health Panel

The CleanPlex® Comprehensive Genetic Health Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing assay for examining the germline variants or mutations across 147 genes associated with Comprehensive Genetic Health.

Product Description

The CleanPlex® Comprehensive Genetic Health Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 147 genes associated with Comprehensive Genetic Health. The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.

This product is made to order. Once we receive your order, we will synthesize the panel and the kit will contain CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.

Storage Temperature

Store at -20 °C.

For Research Use Only. Not for use in diagnostic procedures.

Gene List:
ACTA2, ACTC1, ACTN2, ACVRL1, APC, APOB, ATM, ATP7B, AXIN2, BAG3, BAP1, BARD1, BMPR1A, BMPR2, BRCA1, BRCA2, BRIP1, CACNA1C, CACNA1S, CACNB2, CALM1, CALM2, CALM3, CASQ2, CAV1, CAV3, CDC73, CDH1, CDK4, CDKN2A, CHEK2, COL3A1, CRYAB, CSRP3, DES, DICER1, DMD, DSC2, DSG2, DSP, EMD, ENG, EPCAM, F2, F5, F9, FBN1, FH, FHL1, FLCN, FLNC, GDF2, GLA, GPD1L, GREM1, HAMP, HCN4, HFE, HJV, HOXB13, JUP, KCNE1, KCNE2, KCNH2, KCNJ2, KCNQ1, KIT, LAMP2, LDLR, LDLRAP1, LMNA, MAX, MEN1, MET, MITF, MLH1, MSH2, MSH3, MSH6, MUTYH, MYBPC3, MYH11, MYH7, MYL2, MYL3, MYLK, NBN, NF1, NF2, NKX2-5, NTHL1, OTC, PALB2, PCSK9, PDGFRA, PKP2, PLN, PMS2, POLD1, POLE, PRKAG2, PRKAR1A, PRKG1, PROC, PROS1, PTCH1, PTEN, RAD51C, RAD51D, RB1, RBM20, RET, RYR1, RYR2, SCN5A, SDHA, SDHAF2, SDHB, SDHC, SDHD, SERPINA1, SERPINC1, SGCD, SLC40A1, SMAD3, SMAD4, SMARCA4, SMARCB1, STK11, TCAP, TFR2, TGFB2, TGFB3, TGFBR1, TGFBR2, TMEM127, TMEM43, TNNC1, TNNI3, TNNT2, TP53, TPM1, TSC1, TSC2, VCL, VHL, WT1

References:
Kalia S, et al. Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics. Genet Med 19, 249–255 (2017).

Additional Information

Weight40 g
Dimensions10 x 7 x 5 cm
Pack Size (Reactions)

1000