Amplicon Sequencing in Forensic Science: Solving Crimes with DNA

Amplicon Sequencing in Forensic Science: Solving Crimes with DNA

Amplicon sequencing, powered by next-generation sequencing (NGS), is transforming forensic analysis. By offering precision, efficiency, and the ability to work with even the most difficult DNA fragments, this innovative approach has become a cornerstone of modern forensic science.

How Next-Generation Sequencing (NGS) Has Transformed DNA Testing

Next-generation sequencing has transformed forensic DNA analysis with its ability to provide deeper insights than traditional methods:

• Massive Data Throughput: With massively parallel sequencing, NGS can analyze thousands of genetic regions in a single run, offering unmatched insights.
• Versatility: Supports diverse applications, including DNA profiling, mitochondrial DNA analysis, and microbial forensics.
• Improved Accuracy: Advanced methods like capillary electrophoresis and innovative panel designs ensure high-quality results from challenging samples.

Forensic laboratories can now analyze degraded DNA, trace DNA, and even aged DNA molecules with precision. These advancements make it possible for forensic scientists to revisit cold cases and gather information from previously unusable DNA evidence.

Benefits of Using Custom NGS Panels in Forensics

Custom NGS panels offer customized solutions for forensic laboratories, enhancing the accuracy and efficiency of DNA analysis:

• Precision Targeting: Focuses on regions of DNA most relevant to the investigation, including mitochondrial DNA and STRs.
• Rapid Development: Panels can be delivered in just four weeks, accelerating forensic DNA typing and case resolution.
• Cost-Effectiveness: Optimized workflows reduce costs while preserving high-quality DNA sequencing results.

Why Use Custom NGS Panels Over Standard Forensic DNA Analysis?

While standard DNA fingerprinting methods remain valuable, custom NGS panels provide a level of adaptability that is unmatched. These panels empower forensic laboratories to:

• Extract More Data: Maximize information from degraded DNA fragments and trace DNA samples.
• Tailor Analysis: Focus on specific genetic markers, such as mitochondrial DNA, for unique investigative needs.
• Future-Proof Techniques: Stay ahead of emerging challenges in forensic DNA typing.

Paragon Genomics: Custom-Designed NGS Panels for Forensic Science

At Paragon Genomics, we deliver cutting-edge solutions for forensic DNA analysis with our custom-designed NGS panels. Our panels are developed and delivered in as little as four weeks, enabling rapid DNA analysis for forensic applications. Advanced cleaning chemistry and optimized workflows ensure clean and accurate results.
These panels are customized to address the challenges of degraded DNA, trace samples, and specific forensic needs. Start designing your custom forensic NGS panel today.