CleanPlex® Hereditary Hemochromatosis Panel

The CleanPlex® Hereditary Hemochromatosis Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing assay for examining the germline variants or mutations across 8 genes associated with Hereditary Hemochromatosis.

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Product Description

The CleanPlex® Hereditary Hemochromatosis Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 8 genes associated with Hereditary Hemochromatosis. The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.

This product is made to order. Once we receive your order, we will synthesize the panel and the kit will contain CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.

Storage Temperature

Store at -20 °C.

For Research Use Only. Not for use in diagnostic procedures.

Gene List:
BMP2, FTH1, FTL, HAMP, HFE, HJV, SLC40A1, TFR2

References:
Bryant J. et al. A systematic review of the clinical validity and clinical utility of DNA testing for hereditary haemochromatosis type 1 in at-risk populations. 2008. Journal of Medical Genetics. 45: 513-8. PubMed ID: 18310265

Santos P.C. et al. Molecular diagnostic and pathogenesis of hereditary hemochromatosis. 2012. International Journal of Molecular Sciences. 13: 1497-511. PubMed ID: 22408404

Additional Information

Weight40 g
Dimensions10 x 7 x 5 cm
Pack Size (Reactions)

384

For early access to our upcoming Respiratory Research Panel combining Influenza A/B and SARS-CoV-2 testing, please visit HERE. Dismiss