CleanPlex® Comprehensive Mucopolysaccharidoses (MPS) Panel

The CleanPlex® Comprehensive Mucopolysaccharidoses (MPS) Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing assay for examining the germline variants or mutations across 14 genes associated with Comprehensive Mucopolysaccharidoses (MPS).

Product Description

The CleanPlex® Comprehensive Mucopolysaccharidoses (MPS) Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 14 genes associated with Comprehensive Mucopolysaccharidoses (MPS). The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.

This product is made to order. Once we receive your order, we will synthesize the panel and the kit will contain CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.

Storage Temperature

Store at -20 °C.

For Research Use Only. Not for use in diagnostic procedures.

Gene List:
ARSB, GALNS, GLB1, GNPTAB, GNPTG, GNS, GUSB, HGSNAT, HYAL1, IDS, IDUA, MCOLN1, NAGLU, SGSH

References:
Lowry et al. An update on the frequency of mucopolysaccharide syndromes in British Columbia. Hum Genet 85:389-390, 1990.

Kresse H, et al. The Sanfilippo A corrective factor. Purification and mode of action. J Biol Chem. 1972;247:2164–2170.

Valayannopoulos et al. Mucopolysaccharidosis VI. Orphanet Journal of Rare Diseases 20105:5.

Additional Information

Weight40 g
Dimensions10 x 7 x 5 cm
Pack Size (Reactions)

384