CleanPlex® Peroxisomal Disorders Panel

The CleanPlex® Peroxisomal Disorders Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing assay for examining the germline variants or mutations across 30 genes associated with Peroxisomal Disorders.

Product Description

The CleanPlex® Peroxisomal Disorders Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 30 genes associated with Peroxisomal Disorders. The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.

This product is made to order. Once we receive your order, we will synthesize the panel and the kit will contain CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.

Storage Temperature

Store at -20 °C.

For Research Use Only. Not for use in diagnostic procedures.

Gene List:
ABCD1, ABCD3, ACOX1, AGPS, AGXT, AMACR, CAT, DNM1L, DYM, EBP, GNPAT, HSD17B4, PEX1, PEX10, PEX11B, PEX12, PEX13, PEX14, PEX16, PEX19, PEX2, PEX26, PEX3, PEX5, PEX6, PEX7, PHYH, SCP2, SUGCT, TRIM37

References:
Yoon G, et al. Lethal Disorder of Mitochondrial Fission Caused by Mutations in DNM1L. J Pediatr. 2016 Apr;171:313-6.e1-2.

Braverman NE, et al. Rhizomelic Chondrodysplasia Punctata Type 1. SourceGeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2019. 2001 Nov 16 [updated 2012 Sep 13].

Raymond GV, et al. X-Linked Adrenoleukodystrophy. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2019. 1999 Mar 26 [updated 2018 Feb 15].

Additional Information

Weight40 g
Dimensions10 × 7 × 5 cm
Pack Size (Reactions)

384

CleanPlex Amplicon Sequencing Library Kit Product ImageCleanPlex® Peroxisomal Disorders Panel