CleanPlex® Neurotransmitter Disorders Panel

The CleanPlex® Neurotransmitter Disorders Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing assay for examining the germline variants or mutations across 22 genes associated with Neurotransmitter Disorders.

Product Description

The CleanPlex® Neurotransmitter Disorders Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 22 genes associated with Neurotransmitter Disorders. The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.

This product is made to order. Once we receive your order, we will synthesize the panel and the kit will contain CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.

Storage Temperature

Store at -20 °C.

For Research Use Only. Not for use in diagnostic procedures.

Gene List:
ABAT, ALDH5A1, ALDH7A1, ARHGEF9, DBH, DDC, GAD1, GCH1, GLDC, GLRA1, GLRB, GPHN, MAOA, PCBD1, PHGDH, PNPO, PTS, QDPR, SLC6A3, SLC6A5, SPR, TH

References:
Mei D, et al. The Impact of Next-Generation Sequencing on the Diagnosis and Treatment of Epilepsy in Paediatric Patients. Mol Diagn Ther. 2017 Aug;21(4):357-373.

Narwade SC, et al. Transcriptome Analysis Reveals Altered Expression of Memory and Neurotransmission Associated Genes in the REM Sleep Deprived Rat Brain. Front Mol Neurosci. 2017 Mar 17;10:67.

Additional Information

Weight40 g
Dimensions10 x 7 x 5 cm
Pack Size (Reactions)

384