The CleanPlex® Dystroglycanopathy Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing assay for examining the germline variants or mutations across 18 genes associated with Dystroglycanopathy.
CleanPlex® Dystroglycanopathy Panel
The CleanPlex® Dystroglycanopathy Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 18 genes associated with Dystroglycanopathy. The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.
This product is made to order. Once we receive your order, we will synthesize the panel and the kit will contain CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.
Store at -20 °C.
For Research Use Only. Not for use in diagnostic procedures.
B3GALNT2, B4GAT1, DAG1, DPM1, DPM2, DPM3, FKRP, FKTN, GMPPB, ISPD, LARGE1, POMGNT1, POMGNT2, POMK, POMT1, POMT2, RXYLT1, TMEM5
Roscioli T, et al. Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan. Nat Genet. 2012 May;44(5):581-5.
Barresi R, et al. Dystroglycan: from biosynthesis to pathogenesis of human disease. J Cell Sci. 2006 Jan 15;119(Pt 2):199-207.
|Dimensions||10 x 7 x 5 cm|
|Pack Size (Reactions)|