CleanPlex® Disorders of Fatty Acid Oxidation Panel

The CleanPlex® Disorders of Fatty Acid Oxidation Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing assay for examining the germline variants or mutations across 17 genes associated with Disorders of Fatty Acid Oxidation.

Product Description

The CleanPlex® Disorders of Fatty Acid Oxidation Panel is a pre-designed and made-to-order multiplex PCR / amplicon-based targeted sequencing (NGS) assay designed to examine the germline variants or mutations across 17 genes associated with Disorders of Fatty Acid Oxidation. The panel targets all the exonic regions of those genes and the flanking intronic sequences. Compatible with just 10 ng of DNA, sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The pre-designed panel is optimized in silico to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.

This product is made to order. Once we receive your order, we will synthesize the panel and the kit will contain CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag® Magnetic Beads can be ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.

Storage Temperature

Store at -20 °C.

For Research Use Only. Not for use in diagnostic procedures.

Gene List:
ACADM, ACADS, ACADSB, ACADVL, CPT1A, CPT2, ETFA, ETFB, ETFDH, HADH, HADHA, HADHB, HMGCL, HMGCS2, MLYCD, SLC22A5, SLC25A20

References:
Houten SM, et al. The Biochemistry and Physiology of Mitochondrial Fatty Acid β-Oxidation and Its Genetic Disorders. Annu Rev Physiol. 2016;78:23-44.

van Rijt WJ, et al. Inborn Errors of Metabolism That Cause Sudden Infant Death: A Systematic Review with Implications for Population Neonatal Screening Programmes. Neonatology. 2016;109(4):297-302.

Additional Information

Weight40 g
Dimensions10 × 7 × 5 cm
Pack Size (Reactions)

384

CleanPlex Amplicon Sequencing Library Kit Product ImageCleanPlex® Disorders of Fatty Acid Oxidation Panel