Targeted Sequencing Technologies

Paragon Genomics develops amplicon-based targeted sequencing technologies for DNA and RNA research and agrigenomics. Choose a technology to see how it works and the data behind it.

CleanPlex® Amplicon Sequencing

CleanPlex® is a highly scalable and sensitive NGS amplicon sequencing technology.

  • High amplification uniformity and low PCR background noise for accurate variant calling
  • Single-tube and 3-hour workflow with minimal hands-on time for easy automation
  • Excellent panel size scalability from a few to over 20,000 amplicons in a single multiplex PCR pool

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CleanPlex® UMI

CleanPlex® UMI Technology is an amplicon-based targeted sequencing technology for precise DNA analysis.

  • Unique molecular identifiers (UMIs) enable confident detection of low-frequency variants
  • Proprietary multiplex PCR-based molecular barcoding chemistry uniquely labels each DNA molecule
  • Simple workflow completed in 3.5 hours with only 85 min of hands-on time

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AccuFusion™ RNA Gene Fusion Detection

A targeted multiplex fusion detection technology, built upon CleanPlex® technology, that can also detect novel fusion gene partners.

  • Confident detection of known fusions with the CleanPlex amplicon sequencing chemistry
  • From purified RNA samples to sequencing-ready libraries in 6 hours with about 75 minutes of hands-on time
  • Custom designs and delivery of panels in 3-4 weeks for detecting known fusion genes

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AgriType™ Targeted Genotyping by Sequencing

A cost-effective solution to construct NGS libraries to quickly and efficiently screen hundreds to tens of thousands of markers of interest to accelerate genotyping studies.

  • Target thousands of relevant markers in the same assay
  • Sequencing-ready libraries in just 3 hours using a simple, three-step protocol that can be easily automated
  • Custom assays delivered in 3-4 weeks

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Not Sure Which Technology Fits Your Research?

Our PhD-level expert scientists can help you choose a technology and design the right panel.

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